Hashimoto's thyroiditis pathogenesis pdf

Novel developments in the pathogenesis and diagnosis of. The green arrow points to healthy thyroid gland cells, the orange arrow points to dark purple cells. Risk factors, pathogenesis, signs and symptoms and treatment. It is an autoimmune condition that causes inflammation of. In this condition, immune cells produce antibodies against a key enzyme that is required for thyroid hormone production thyroid peroxidase andor against thyroglobulin, which is the building block of thyroid hormones. Adults present with painless, gradual thyroid failure due to autoimmune destruction, may initially have transient hyperthyroidism. Hashimotos thyroiditis ht is an autoimmune disorder characterized by diffuse thyroid lymphocytic infiltration and follicle destruction. It is an autoimmune disorder involving chronic inflammation of the thyroid. Hashimotos thyroiditis is also known as chronic lymphocytic thyroiditis or autoimmune thyroiditis.

Also called hashimotos disease, hashimotos thyroiditis is an autoimmune disease, a disorder in which the immune system turns against the bodys own tissues. The term thyroiditis refers to inflammation of the thyroid gland. If hashimoto s thyroiditis causes cell damage leading to low thyroid hormone levels, patients will eventually develop symptoms of hypothyroidism see hypothyroidism brochure. But till now it is still enigmatic disease with not so well known causes and etiology. The pathogenesis of hashimotos thyroiditis thieme connect. Hashimotos thyroiditis ht and graves disease gd are two very common organspecific autoimmune diseases which are characterized by circulating. Risk factors and pathogenesis of hashimotos thyroiditis. The autoimmune chronic thyroiditis or hashimotos thyroiditis ht is an. Hashimotos thyroiditis ultrasound image of thyroid gland, exam was done for suspicion of nodules on the gland, us revealed diffuse hashimotos with no presence of nodules2 this is a picture of a patient with hashimotos. Thyroid failure is seen in up to 10 percent of the population, and its prevalence increases with age 1. Hashimoto s thyroiditis, also known as chronic lymphocytic thyroiditis, is the most common cause of hypothyroidism in the united states. At the base of the pathology there is an inflammatory.